Examining infants' visual paired comparison performance in the US and rural Malawi.

Measures of attention and memory were evaluated in 6- to 9-month-old infants from two diverse contexts. One sample consisted of African infants residing in rural Malawi (N = 228, 118 girls, 110 boys). The other sample consisted of racially diverse infants residing in suburban California (N = 48, 24 girls, 24 boys). Infants were tested in an eye-tracking version of the visual paired comparison procedure and were shown racially familiar faces. The eye tracking data were parsed into individual looks, revealing that both groups of infants showed significant memory performance. However, how a look was operationally defined impacted some-but not other-measures of infant VPC performance. RESEARCH HIGHLIGHTS: In both the US and Malawi, 6- to 9-month-old infants showed evidence of memory for faces they had previously viewed during a familiarization period. Infant age was associated with peak look duration and memory performance in both contexts. Different operational definitions of a look yielded consistent findings for peak look duration and novelty preference scores-but not shift rate. Operationalization of look-defined measures is an important consideration for studies of infants in different cultural contexts.

A Novel Approach to Assessing Infant and Child Mental Rotation.

Mental rotation is a critically important, early developing spatial skill that is related to other spatial cognitive abilities. Understanding the early development of this skill, however, requires a developmentally appropriate assessment that can be used with infants, toddlers, and young children. We present here a new eye-tracking task that uses a staircase procedure to assess mental rotation in 12-, 24-, and 36-month-old children (N = 41). To ensure that all children understood the task, the session began with training and practice, in which the children learned to fixate which of two houses a giraffe, facing either left or right, would approach. The adaptive two-up, one-down staircase procedure assessed the children's ability to fixate the correct house when the giraffe was rotated in 30° (up) or 15° (down) increments. The procedure was successful, with most children showing evidence of mental rotation. In addition, the children were less likely to succeed as the angle of rotation increased, and the older children succeeded at higher angles of rotation than the younger children, replicating previous findings with other procedures. The present study contributes a new paradigm that can assess the development of mental rotation in young children and holds promise for yielding insights into individual differences in mental rotation.

An investigation of mental rotation in infancy using change detection.

Two experiments were conducted to examine mental rotation in 6- to 12-month-old infants (N = 166) using a change detection task. These experiments were replications of Lauer and Lourenco (Lauer et al., 2015; Lauer & Lourenco, 2016), using identical stimuli and variations of their procedure, including an exact replication conducted in a laboratory setting (Experiment 1), and an online assessment using Lookit (Scott et al.,2017; Scott & Schulz, 2017) (Experiment 2). Both experiments failed to replicate the results of the original study; in neither experiment did infants' behavior provide evidence that they mentally rotated the object. Results are discussed in terms of the robustness of mental rotation in infancy and about limits in our experimental procedures for uncovering perceptual and cognitive abilities in infants.

The association between plasma choline, growth and neurodevelopment among Malawian children aged 6-15 months enroled in an egg intervention trial.

Choline is an essential micronutrient that may influence growth and development; however, few studies have examined postnatal choline status and children's growth and development in low- and middle-income countries. The aim of this observational analysis was to examine associations of plasma choline with growth and development among Malawian children aged 6-15 months enrolled in an egg intervention trial. Plasma choline and related metabolites (betaine, dimethylglycine and trimethylamine N-oxide) were measured at baseline and 6-month follow-up, along with anthropometric (length, weight, head circumference) and developmental assessments (the Malawi Developmental Assessment Tool [MDAT], the Infant Orienting with Attention task [IOWA], a visual paired comparison [VPC] task and an elicited imitation [EI] task). In cross-sectional covariate-adjusted models, each 1 SD higher plasma choline was associated with lower length-for-age z-score (-0.09 SD [95% confidence interval, CI -0.17 to -0.01]), slower IOWA response time (8.84 ms [1.66-16.03]) and faster processing speed on the VPC task (-203.5 ms [-366.2 to -40.7]). In predictive models, baseline plasma choline was negatively associated with MDAT fine motor z-score at 6-month follow-up (-0.13 SD [-0.22 to -0.04]). There were no other significant associations of plasma choline with child measures. Similarly, associations of choline metabolites with growth and development were null except higher trimethylamine N-oxide was associated with slower information processing on the VPC task and higher memory scores on the EI task. In this cohort of children with low dietary choline intake, we conclude that there were no strong or consistent associations between plasma choline and growth and development.

Linking patterns of infant eye movements to a neural network model of the ventral stream using representational similarity analysis.

Little is known about the development of higher-level areas of visual cortex during infancy, and even less is known about how the development of visually guided behavior is related to the different levels of the cortical processing hierarchy. As a first step toward filling these gaps, we used representational similarity analysis (RSA) to assess links between gaze patterns and a neural network model that captures key properties of the ventral visual processing stream. We recorded the eye movements of 4- to 12-month-old infants (N = 54) as they viewed photographs of scenes. For each infant, we calculated the similarity of the gaze patterns for each pair of photographs. We also analyzed the images using a convolutional neural network model in which the successive layers correspond approximately to the sequence of areas along the ventral stream. For each layer of the network, we calculated the similarity of the activation patterns for each pair of photographs, which was then compared with the infant gaze data. We found that the network layers corresponding to lower-level areas of visual cortex accounted for gaze patterns better in younger infants than in older infants, whereas the network layers corresponding to higher-level areas of visual cortex accounted for gaze patterns better in older infants than in younger infants. Thus, between 4 and 12 months, gaze becomes increasingly controlled by more abstract, higher-level representations. These results also demonstrate the feasibility of using RSA to link infant gaze behavior to neural network models. A video abstract of this article can be viewed at https://youtu.be/K5mF2Rw98Is.

Infant Eye Gaze While Viewing Dynamic Faces.

Research using eye tracking methods has revealed that when viewing faces, between 6 to 10 months of age, infants begin to shift visual attention from the eye region to the mouth region. Moreover, this shift varies with stimulus characteristics and infants' experience with faces and languages. The current study examined the eye movements of a racially diverse sample of 98 infants between 7.5 and 10.5 months of age as they viewed movies of White and Asian American women reciting a nursery rhyme (the auditory component of the movies was replaced with music to eliminate the influence of the speech on infants' looking behavior). Using an analytic approach inspired by the multiverse analysis approach, several measures from infants' eye gaze were examined to identify patterns that were robust across different analyses. Although in general infants preferred the lower regions of the faces, i.e., the region containing the mouth, this preference depended on the stimulus characteristics and was stronger for infants whose typical experience included faces of more races and for infants who were exposed to multiple languages. These results show how we can leverage the richness of eye tracking data with infants to add to our understanding of the factors that influence infants' visual exploration of faces.

Visual short-term memory for overtly attended objects during infancy.

We investigated limitations in young infants' visual short-term memory (VSTM). We used a one-shot change detection task to ask whether 4- and 8.5-month-old infants (N = 59) automatically encode fixated items in VSTM. Our task included trials that consisted of the following sequence: first a brief (500 ms) presentation with a sample array of two items, next a brief (300 ms) delay period with a blank screen, and finally a test array (2,000 ms) identical to the sample array except that the color of one of the two items is changed. In Experiment 1, we induced infants to fixate one item by rotating it during the sample (the other item remained stationary). In Experiment 2, none of the items rotated. In both experiments, 4-month-old infants looked equally at the fixated item when it did and did not change color, providing no evidence that they encoded in VSTM the fixated item. In contrast, 8.5-month-old infants in Experiment 1 preferred the fixated item when it changed color from sample to test. Thus, 4-month-old infants do not appear to automatically encode fixated items in VSTM.